Research Associate m/f/d, Basel-StadtWe are looking for a highly motivated and skilled Research Associate to join our client's dynamic Rare Blood Disorders team. This role plays a key part in evaluating the efficacy, safety, and translatability of innovative therapeutic strategies in non-malignant hematological disorders, with a primary focus on hemoglobinopathies.
You will be part of a collaborative, international group of scientists and research associates advancing next-generation treatments. Your work will involve in vitro experimentation using patient-derived and primary cells, as well as ex vivo studies using animal models. The ideal candidate thrives in a collaborative environment, brings technical depth in molecular biology and cell-based assays, and possesses experience working with rodent models.
Location: Basel, Switzerland
Workload: 80-100%
Contract Duration: 18 months (extension possible)
Start Date: ASAP (no later than 01.10.2025)
Work Type: On-site with limited hybrid flexibility
Key Responsibilities:
- Conduct animal handling and experimentation in transgenic mouse models (e.g., injections, tissue collection, processing)
- Perform downstream ex vivo analyses using flow cytometry, qPCR, western blotting, and other molecular techniques
- Culture and manipulate cell lines and primary/patient-derived samples to assess therapeutic interventions
- Design, execute, and analyze experiments in close collaboration with internal scientific teams
- Contribute to the optimization of existing protocols and the development of novel assays
Must-Have Qualifications:
- BSc or MSc in Life Sciences (e.g., Cell/Molecular Biology, Hematology, Immunology, Pharmacology) or equivalent apprenticeship ("Lehrabschluss") with 3+ years of experience
- Valid authorization for animal experimentation (LTK1, FELASA, or equivalent)
- Demonstrated hands-on experience in rodent handling and tissue processing (e.g., injections, sample collection)
- Strong proficiency in cell culture and molecular assays (e.g., qPCR, western blot)
Nice to Have:
- Experience in multi-color flow cytometry
- Background in hematopoiesis or immunology (theoretical or technical knowledge)
- Previous experience in a pharmaceutical or biotech industry setting
Note: Candidates holding a PhD will be considered overqualified for this role.
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